Kristi Baker, PhD
Department of Experimental Oncology
Cross Cancer Institute and University of Alberta
11560 University Avenue , Rm 3334
Edmonton, Alberta T6G 1Z2, Canada
I am Courtney Mowat, a second year Master's student in Cancer Science at the University of Alberta. I have been working in Kristi's lab since 2015 as a summer student and then for my undergraduate thesis. I completed my undergraduate degree in honors molecular genetics at the UofA, where I got to learn about how awesome gene regulation is and that it could be manipulated using biological tools that are already found in nature. This made me a perfect fit for Kristi's lab, because cancer is essentially gene regulation gone wrong and I get to use genetic tools to create models for studying cancer biology. My project is looking at how genetic instability impacts the mucosal immune system of the gut to influence the development of colorectal cancer. One of the major aims of my thesis is to determine whether tumours with mutations in different DNA repair pathways influences the species of bacteria that reside in the gut and if we can alter the progression of these tumours by introducing certain microbes. If so, then we can dig into what signalling pathways these microbes are stimulating, illuminating possible therapeutic targets.
Hi, my name is Isaac Menghisteab. I completed my undergraduate degree in molecular genetics at the University of Alberta. I’m now a graduate student in the Baker Lab at the Cross Cancer Institute. My research interests lie in colorectal cancer progression and the and interaction of colorectal cancer with the immune system.
Hi! I'm Jianyin and I'm currently completing my undergrad in Immunology and Infection. My project focuses on the interaction between gut microbes and genetic instability in anti-colon cancer immunity, mainly focusing on pks+ and pks- E. coli, where the pks island can lead to secretion of colibactin, a genotoxin that causes DNA double strand break. pks+ E. coli strains are often associated with CRC.
Apart from being a science enthusiast, I enjoy traveling, exploring all the hidden gems (I am still in search of the best cafe in town) or simply reading (may include scientific journals), watching movies and eating pizza. I'm in the process of learning German, where 'ausgezeichnet' is my favourite word, because everything (especially in our lab) is excellent!
Interesting things to note about me:
Fox is my favourite animal. I label all my tubes/plates/everything with blue sharpies and blue sharpies only. Pipette tips should be used in certain orders.
Interested in joining the team?